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Vol. 61 (2006)

Articles

Antifungal efficacy of oxythiamine – antivitamin derivative of vitamin B1

Submitted: February 3, 2021
Published: 2006-12-31

Abstract

The in vitro antifungal activity (MIC, MFC) of oxythiamine was assessed against 15 dermatophyte strains, 9 moulds and 24 yeast-like fungi. High activity of oxythiamine was determined towards Malassezia pachydermatis strains (n = 10); in this case MIC was found within 1.25–2.5 g ml-1. The biocidal efficacy (MFC) of oxythiamine was not recorded in any drug dose applied.

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