Two field experiments were carried out in the experimental farm, in El-Khattara region, Sharkia Governorate, Egypt during 1997/98 and 1998/99 seasons. The first experiment studied the effect of three nitrogen fertilizer leavels and Cerealin (N-biofertizer) on growth and grain yield of three wheat cultivars (Triticum aestivum L.). The second experiment investigated the influence of three micronutrients (Fe, Zn, and Mn) as well as their combinations and Nutrichem (foliar fertilizer) on some yield attributes and grain yield of wheat (Sakha 8 cultivar). In the first experiment Gemmeiza 3 cultivar recorded the highest dry weight of plant, largest flag leaf area and produced the highest grain yield in comparison with Sakha 69 and Sakha 8 (the last cultivar had the lowest values of analized traits). Irrespectively of cultivars, N-fertilization significantly increased dry weight of plants, flag leaf area and yield of grain (up to dose of 238 kg N/ha). In all cultivars the N-biofertilizer (Cerealin) showed positive effect on plants dry mass weight, flag leaf area, and grain yield. In the second experiment addition of Fe + Zn + Mn as well as foliar application of Nutrichem increased significantly 1000 grain weight and grain yield. KEY WORDS: wheat, N fertilization, micronutrients, grain yield.