Skip to main navigation menu Skip to main content Skip to site footer

Vol. 15 No. 4 (2016)

Articles

CONTENT OF ALKALOIDS AND FLAVONOIDS IN CELANDINE (Chelidonium majus L.) HERB AT THE SELECTED DEVELOPMENTAL PHASES

Submitted: October 29, 2020
Published: 2016-08-31

Abstract

The content of alkaloids and flavonoids and the yield of herb were analyzed in greater celandine cultivar ‘Cynober’ during six following phases: spring rosette for-mation, the beginning of flowering, full bloom, green fruit, seed harvest, fall rosette formation. Yield of celandine herb was different at the investigated phases and in years of cultivation. The highest yield of herb was observed at the beginning of flowering, then a decrease was noticed, up to the phase of seed harvest, when the yield grown up. The low-est yield of celandine herb was obtained in last phase – fall rosette formation, except 2011 when the lowest yield was in spring rosette formation. The average content of alkaloids was the highest in phase of green fruit (1.097%), while in 2012, the highest content was reached in phase of fall rosette formation – 1.200%. The lowest content of alkaloids was obtained in herb of the beginning of flowering (0.608%) in both years. The mean content of flavonoids was from 0.310% (the beginning of flowering) to 0.522% (seed harvest) and was the same in both years. The stable high content of total alkaloids and flavonoids and individual alkaloids was noticed in phase of fall rosette. Our results suggest that seed maturity is the best time for celandine herb harvest regarding the herb yield and content of alkaloids and flavonoids.

References

Bugatti, C., Colombo, M.L., Tome, F. (1987). High-performance liquid chromatographic separation of quaternary alkaloids of Chelidonium majus L. roots. J. Chrom., 393, 312–316.
Colombo, M.L., Bosisio, E. (1996). Pharmacological activities of Chelidonium majus L. (Papaveraceae). Pharm. Res., 33(2), 127–134.
De Rosa, S., di Vincenzo, G. (1992). Isochelidonine, a benzophenanthridine alkaloid from Chelidonium majus. Phytochemistry, 31(3), 1085–1086.
European Pharmacopoeia VI (2008). Monograph of greater celandine. Monograph of birch leaf, vol. 1. Council of Europe, Strasbourg.
Fik, E., Dalgalarrondo, M., Haertle, T., Goździcka-Józefiak, A. (2000). Comparative biochemical analysis f lecitin and niclease from Chelidonium majus L. Acta Biochim. Polon., 47(2), 413–420.
Fulde, G., Wichtl, M. (1994). Analytik von Schollkraut. Deut. Apoth. Zeit., 135, 1031–1035.
Garcia, V.P., Valdes, F., Martin, R., Luis, J.C., Afonso, A.M., Ayala, J.H. (2006). Biosynthesis of antitumoral and bactericidal sanguinarine. J. Biomed. Biotech., 24, 1–6.
Gerenčer, M., Turecek, P.L., Kistner, O., Mitterer, A., Savidis-Dacho, H., Barrett, N.P. (2006). In vitro and in vivo antiretroviral activity of the subsance purified from aqueous extract of Chelidonium majus L. Antivir. Res., 72(2), 153–156.
Gertig, H., Frenclowa, I., Alkiewicz, J., Janiakowa, E. (1957). Fungistatical activity of some substances isolated from greater celandine (Chelidonium majus L.). Acta Pol. Pharm., 14, 101–108 (in Polish).
Hahn, R., Nahrstedt, A. (1993). Hydroxycinnamic acid derivatives, caffeoylmalic and new caffeoylaldonic acid esters from Chelidonium majus. Planta Med., 59, 71–75.
Horváth, G., Molnár, P., Farkas, A., Szabó, L., Turcsi, E., Deli, J. (2010). Separation and identification of carotenoids in flowers of Chelidonium majus L. and inflorescences of Solidago canadensis L. Chromatogr., 67, 1–6.
Kèry, A., Horváth, J., Nász, L., Verzár-Petri, G., Kulcsár, G., Dán, P. (1987). Antiviral alkaloid in Chelidonium majus L. Acta Pharm. Hung., 57(1–2), 19–25.
Kędzia, B., Hołderna-Kędzia, E., Goździcka-Józefiak, A., Buchwald, W. (2013). The antimicro-bial activity of Chelidonium majus L. Post. Fitoter., 4, 236–243 (in Polish).
Kohlmünzer, S. (2000). Farmakognozja. Warszawa PZWL., 450–451.
Kopytko, Y.F., Dargaeva, T.D., Sokoloskaya, T.A., Grodnitskaya, E.I., Kopnin, A.A. (2005). New methods for the quality control of a homeopathic matrix tincture of greater celandine. Pharm. Chem. J., 39(11), 603–609.
Kozak, M., Bocianowski, J., Rybiński, W. (2013). Note on the use of coefficient of variation for data from agricultural factorial experiments. Bulgar. J. Agricult. Sci., 19(4), 644–646.
Kucharski, W. (2010). Glistnik jaskółcze ziele. In: Uprawa ziół poradnik dla plantatorów, Kołodziej, B. (eds.). PWRiL, Poznań, 179–183.
Kustrak, D., Petricic, J., Kolodera, Z. (1982). Seasonal changes of alkaloid contents in celandine (Chelidonium majus L.). Acta Pharm. Jugosl., 32, 225–230.
Kwasniewski, V. (1958). Untersuchungen über die nichtalkaloidschen Inhaltstoffe des Schöll-krauts (Chelidonium majus L.). Pharmazie, 13, 3363–3364.
Matos, O.C., Baeta, J., Silva, M.J., Pinto Ricardo, C.P. (1999). Sensitivity of Fusarium strains to Chelidonium majus L. extracts. J. Ethnopharmacol., 66, 151–158.
Migas, P., Heyka, M. (2011). Celandine (Chelidonium majus L.) in modern therapy – indications and safety of use. Post. Fitoter., 2, 1–14 (in Polish).
Nawrot, R., Leśniewicz, K., Pienkowska, J., Goździcka-Józefiak, A. (2007). A novel extracellular peroxidase and necleases from milky sap of Chelidonium majus. Fitoter., 78, 496–501.
Polish Pharmacopea IX (2011). Chelidonii herba, vol. 1. PTF. Warszawa, 1239–1240.
Sárközi, A., Janicsák, G., Kursinszki, L., Kéry, Á. (2006). Alkaloid composition of Chelidonium majus L. studied by different chromatographic techniques. Chromatogr. Suppl., 63, 81–86.
Shapiro, S.S., Wilk, M.B. (1965). An analysis of variance test for normality (complete samples). Biometrika, 52, 591–611.
Slavik, J., Slavikova, L. (1977). Minor alkaloids from Chelidonium majus L. Collect. Czechoslov. Chem. Commun., 42, 2686–2693.
Stancic-Rotaru, M., Mititelu, M., Crasmaru, M., Balaban, D. (2003). Spectroanalytical profile of flavonoids from Chelidonium majus L. Roum. Biotechnol. Lett., 8, 1093–1100.
Tamas, M., Chindris, E., Tuia, R.M. (1987). Investigations on the alkaloids in Chelidonium majus L. Cluj. Med., 60(3), 256–260 (in Rumanian).
Tan, G.T., Pezzuto, J.M., Kinghorn, A.D. (1991). Evaluation of natural products as inhibitors of human immunodefieciency virus type 1 (HIV-1) reverse transcriptase. J. Nat. Prod., 54(1), 143–154.
Tomè, F., Colombo, M.L. (1995). Distribution of alkaloids in Chelidonium majus and factors affecting their accumulation. Phytochem., 40(1), 37–39.
VSN International (2014). GenStat Reference Manual (Release 17). VSN International, Hemel Hempstead, UK.

Downloads

Download data is not yet available.

Most read articles by the same author(s)

Similar Articles

<< < 19 20 21 22 23 24 25 26 27 28 > >> 

You may also start an advanced similarity search for this article.