BIOACTIVE  COMPOUNDS,  ANTIBACTERIAL  AND  ANTIFUNGAL  ACTIVITIES  OF  TWO  Cirsium  SPECIES

Dumrul Gulen; Temine Sabudak; Hakime H. Orak; Hilmican Caliskan; Merve Ozer

doi:10.24326/asphc.2019.5.21

Vol. 18 No. 5 (2019)

Articles

BIOACTIVE COMPOUNDS, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF TWO Cirsium SPECIES

Dumrul Gulen⁺⁻
Temine Sabudak⁺⁻
Hakime H. Orak⁺⁻
Hilmican Caliskan⁺⁻
Merve Ozer⁺⁻

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DOI: https://doi.org/10.24326/asphc.2019.5.21
Submitted: October 30, 2019
Published: 2019-10-30

Abstract

In the GC-MS analysis, 81 bioactive phytochemical compounds were identified in the hexane extracts of Cirsium creticum and Cirsium italicum. Terpenoids constituted the main fractions of C. italicum (70.95 %) while hydrocarbons were most abundant compounds of C. creticum (41.11 %). The antibacterial activity and antifungal activity of extracts from two Cirsium species was tested by using microdilution methods. According to the results of antibacterial activity, highest inhibition effect of C. creticum was found on B. subtilis, E. coli and P. aeruginosa. The highest inhibition effect of C. italicum was found on B. subtilis. In the results of antifungal activity, highest inhibition effect of C. creticum was found on P. chrysogenum and highest inhibition effect of C. italicum was found on C. krusei. The present work is the first report on hexane extracts compounds of two Cirsium species as well as the antibacterial and antifungal activities.

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