Abstrakt
Szałwia lekarska (Salvia officinalis L.) ma długą historię stosowania w kuchni i medycynie tradycyjnej. W Europie stosowana była w leczeniu łagodnej dyspepsji, nadmiernej potliwości, związanych z wiekiem zaburzeń poznawczych oraz stanów zapalnych gardła i skóry. Współczesne badania potwierdziły zasadność tradycyjnego użytkowania szałwii, a także ujawniły szeroki zakres działania farmakologicznego jej składników aktywnych, w tym działanie przeciwrakowe, przeciwzapalne, przeciwnonyceptywne, przeciwutleniające, przeciwbakteryjne, przeciwmutagenne, hipoglikemiczne i hipolipidemiczne. Aktywną grupę składników ziela szałwii stanowią: olejek eteryczny zawierający borneol, kamforę, kariofilen, 1,8-cyneol, elemen, humulen, pinen i α-i β-tujon, a także związki polifenolowe, w tym: kwasy fenolowe oraz flawonoidy oraz związki terpenowe.
Bibliografia
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- Climati E., Mastrogiovanni F., Valeri M., Salvini L., Bonechi C., Zokirzhonovn Mamadalieva N., Egamberdieva D., Taddei A.R., Tiezzi A., 2013. Methyl carnosate, an antibacterial diterpene isolated from Salvia officinalis leaves. Nat. Prod. Comm. 8(4), 429–430.
- Conde-Hernández L. A., Luna-Guevara M. L., Luna-Guevara J. J., Pérez-Vázquez J., Aranda-García R. J., 2021. Mexican sage (Salvia officinalis) extraction using factorial design and its ef-fect on chemical and antibacterial properties. J. Chem. https://doi.org/10.1155/2021/5594278
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- Delamare A.P.L., Moschen-Pistorello I.T., Artico L., Atti-Serafini L., Echeverrigaray S., 2007. Antibacterial activity of the essential oils of Salvia officinalis L. and Salvia triloba L. cultivated in South Brazil. Food Chem. 100, 603–608. http://dx.doi.org/10.1016/j.foodchem.2005.09.078
- Duletić-Laušević S., Alimpić Aradski A., Šavikin K., Knežević A., Milutinović M., Stević T., Vukojević J., Marković S., Marin P.D., 2018. Composition and biological activities of Libyan Salvia fruticosa Mill. and S. lanigera Poir. extracts. S. Afr. J. Bot. 117, 101–109. https://doi.org/10.1016/j.sajb.2018.05.013
- El-Sayed E., EI-Serwyl M., Abd EI-Hameid M.A., 2012. Influence of sage (Salvia officinalis L.) and purslane (Portulaca oleracea L.) on weight reduction and some biochemical parameters in rats suffering from obesity. Egypt. J. Nutr. Health 7(1), 15–30.
- Fatima N., Tabassum A., 2020. Effect of Salvia officinalis on neuromodulating and oxidative stress status in brain of male albino wistar rats intoxicated with aluminium. Acta Pharm. Sci. 58(3), 277–304. https://doi.org/10.23893/1307-2080.APS.05816
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- Grdiša M., Jug-Dujaković M., Lončarić M., Carović-Stanko K., Ninčević T., Liber Z., Ra-doslavljević I., Šatović Z., 2015. Dalmatian sage (Salvia officinalis L.): A review of biochemical contents, medical properties and genetic diversity. Agric. Conspec. Sci. 80(2), 69–78.
- Hać-Szymańczuk E., Lipińska E., Błażejak S., Bieniak K., 2011. Ocena aktywności przeciwbakte-ryjnej szałwii lekarskiej (Salvia officinalis L.). Bromat. Chem. Toksykol. 44(3), 667–672.
- Hamidpour M., Hamidpour R., Hamidpour S., Shahlari M., 2014. Chemistry, pharmacology, and medicinal property of sage (Salvia) to prevent and cure illnesses such as obesity, diabetes, de-pression, dementia, lupus, autism, heart disease, and cancer. J. Tradit. Complement. Med. 4(2), 82–88. http://dx.doi.org/10.4103/2225-4110.130373
- Jasicka-Misiak I., Poliwoda A., Petecka M., Buslovych O., Shlyapnikov V.A., Wieczorek P.P., 2018. Antioxidant phenolic compounds in Salvia officinalis L. and Salvia sclarea L. Ecol. Chem. Eng. S. 25(1), 133–142. http://dx.doi.org/10.1515/eces-2018-0009
- Kačaniová M., Galovičova L., Valkova V., Ďuranova H., Borotova P., Štefanikova J., Vukovic N.L., Vukic M., Kunova S., Felsociova S., Miklašova K., Savitskaya T., Grinshpan D., 2021. Chemical composition and biological activity of Salvia officinalis essential oil. Acta Hort. Re-giotec. 24(2), 81–88. http://dx.doi.org/10.2478/ahr-2021-0028
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- Kermanshah H., Kamangar S.H., Arami S., Mirsalehian A., Kamalineghad M., Karimi M., 2009. In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimp-inella anisum against cariogenic bacteria. J. Dent. Med. 22, 149–154.
- Khalil R., Li Z.-G., 2011. Antimicrobial activity of essential oil of Salvia officinalis L. collected in Syria. Afr. J. Biotechnol. 10(42), 8397–8402. http://dx.doi.org/10.5897/AJB10.2615
- Khan A., Rehman N., AlKharfy K.M., Gilani A.H., 2011. Antidiarrheal and antispasmodic activities of Salvia officinalis are mediated through activation of K+ channels. Bangladesh J. Pharmacol. 6, 111–116.
- Miazgowski T., 2012. Otyłość a cukrzyca. Fam. Med. Prim. Care Rev. 14(3), 462–467.
- Ninomiya K., Matsuda H., Shimoda H., Nishida N., Kasajima N., Youshino T., 2004. Carnosic acid, a new class of lipid absorption inhibitor from sage. Bioorg. Med. Chem. Lett. 14, 1943–1946.
- Miladinović D., Miladinović L., 2000. Antimicrobial activity of essential oil of sage from Serbia. Facta Univ., Phys. Chem. Technol. 2(2), 97–100.
- Mohammed H.A., Eldeeb H.M., Khan R.A., Al-Omar M.S., Mohammed S.A.A., Sajid M.S.M., Aly M.S.A., Ahmad A.M., Abdellatif A.A.H., Eid S.Y., El-Readi M.Z., 2021. Sage, Salvia of-ficinalis L., constituents, hepatoprotective activity, and cytotoxicity evaluations of the eesential oils obtained from fresh and differently timed dried herbs: A comparative analysis. Molecules 26, 5757. https://doi.org/10.3390/molecules26195757
- Musiał K., 2017. Rośliny lecznicze w najwcześniejszych dokumentach wiedzy medycznej. Rozpr. Społ. 11(4), 56–63.
- de Oliveira J.R., das Graças Figueiredo Vilela P., de Aguiar Almeida R.B., de Oliveira F.E., Carvalho C.A.T., Camargo S.E.A., Cardoso Jorge A.O., de Oliveira L.D., 2019. Antimicrobial activity of noncytotoxic concentrations of Salvia officinalis extract against bacterial and fungal species from the oral cavity. Gen. Dent. 434, 22–26.
- Rešetnik I., Baričevič D., Batîr Rusu D., Carović-Stanko K., Chatzopoulou P., Dajić-Stevanović Z., Gonceariuc M., Grdišan M., Greguraš D., Ibraliu A., Jug-Dujaković M., Krasniqi E., Liber Z., Murtić S., Pećanac D., Radosavljević I., Stefkov G., Stešević D., Šoštarić I., Šatović Z., 2016. Genetic diversity and demographic history of wild and cultivated/naturalised plant populations: Evidence from dalmatian sage (Salvia officinalis L., Lamiaceae). PLoS ONE 11(7). https://doi.org/10.1371/journal.pone.0159545
- Sellami I.H., Rebey I.B., Sriti J., Rahali F.Z., Limam F., Marzouk B., 2012. Drying sage (Salvia officinalis L.) plants and its effects on content, chemical composition, and radical scavenging ac-tivity of the essential oil. Food Bioprocess Technol. 5, 2978–2989.
- Stanojević D., Čomić L., Stefanović O., Solujić-Sukdolak S., 2010. In vitro synergistic antibacterial activity of Salvia officinalis L. and some preservatives. Arch. Biol. Sci., Belgrade 62(1), 175–183. https://doi.org/10.2298/ABS1001175P
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- Stefanović O., Stanojević D., Čomić L., 2012. Synergistic antibacterial activity of Salvia officinalis L. and Cichorium intybus extracts and antibiotics. Acta Pol. Pharm., Drug Res. 69(3), 457–463.
- Tosun A., Khan S., Kim Y.S., Calín-Sánchez Á., Hysenaj X., Carbonell-Barrachina Á.A., 2014. Essential oil composition and anti-inflammatory activity of Salvia officinalis L (Lamiaceae) in murin macrophages. Trop. J. Pharm. Res. 13(6), 937–942. http://dx.doi.org/10.4314/tjpr.v13i6.16
- Tundis R., Leporini M., Bonesi M., Rovito S., Passalacqua N.G., 2020. Salvia offcinalis L. from Italy: A comparative chemical and biological study of its essential iil in the Mediterranean con-text. Molecules 25, 5826. http://dx.doi.org/10.3390/molecules25245826
- Vissi T., Zelkó R., Földesi R., Túri I., 2021. Traditional application of Sage (Salvia) in conductive education and its potential evidence – based background. Heliyon 7. https://doi.org/10.1016/j.heliyon.2021.e08114
- Walch S.G., Kuballa T., Stühlinger W., Lachenmeier D.W., 2011. Determination of the biologically active flavour substances thujone and camphor in foods and medicines containing sage (Salvia officinalis L.). Chem. Central J. 5, 44.
- Wilfried D., Nina C.D.G., Silvia B., 2021. Effectiveness of Menosan® Salvia officinalis in the treatment of a wide spectrum of menopausal complaints. A double-blind, randomized, placebo-controlled, clinical trial. Heliyon 7, e05910. https://doi.org/10.1016/j.heliyon.2021.e05910
- Zaccardelli M., Pane C., Caputo M., Durazzo A., Lucarini M., Silva A.M., Severino P., Souto E.B., Santini A., De Feo V., 2020. Sage species case study on a spontaneous Mediterranean plant to control phytopathogenic fungi and bacteria. Forests 11, 704. http://dx.doi.org/10.3390/f11060704
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- Zawiślak G., 2014. Yield and chemical composition of essential oil from Salvia officinalis L. in third year of cultivation. Herba Pol. 60(3), 13–22. https://doi.org/10.2478/hepo-2014-0012
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