Agnieszka Szopa

Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland

Marta Klimek-Szczykutowicz

Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland

Karolina Jafernik

Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland

Katarzyna Koc

Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland

Halina Ekiert

Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland


The flower (inflorescence, basket-type inflorescence) of marigold (Calendulae officinalis flos) is a well-known plant raw material in traditional phytomedicine. Noteworthy is its rich chemical composition, which is dominated by flavonoids and terpenoids. Terpenoids are mainly represented by specific for this species oleanolic acid derivatives: triterpenoid saponins – calendulosides A-H and triterpenoid glycosides, so-called calendulaglycosides A and B. The biological activity profiles of the raw material, such as anti-inflammatory, antimicrobial, immunostimulatory and antioxidant properties, determine its use especially in the treatment of dermatological diseases. Interestingly, recent scientific studies proved, in addition to spasmolitic, hypolipemic and antidiabetic properties, such heath promoting activity as cardioprotective, hepatoregenerative, pancreas regenerating, neuroprotective and even anticancer activities. Moreover, C. officinalis is used in cosmetology and food industry.


marigold, medicinal plant, chemical composition, therapeutic properties, cosmetic application

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Agnieszka Szopa 
Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland
Marta Klimek-Szczykutowicz 
Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland
Karolina Jafernik 
Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland
Katarzyna Koc 
Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland
Halina Ekiert 
Chair and Department of Pharmaceutical Botany, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Kraków, Poland



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