HARNESSING THE POTENTIAL OF NOVEL BIOACTIVE COMPOUNDS PRODUCED BY ENDOPHYTIC Phoma spp. – BIOMEDICAL AND AGRICULTURAL APPLICATIONS

Mahendra Rai

Department of Biotechnology, SGB Amravati University, Amravati-444602, Maharashtra, India
https://orcid.org/0000-0003-0291-0422

Aniket Gade

Department of Biotechnology, SGB Amravati University, Amravati-444602, Maharashtra, India
https://orcid.org/0000-0002-1966-999X

Beata Zimowska

Department of Plant Protection, Institute of Plant Pathology and Mycology, University of Life Sciences in Lublin, 7 K. St. Leszczyńskiego Street, 20-068 Lublin, Poland
https://orcid.org/0000-0001-5524-7623

Avinash P. Ingle

Department of Biotechnology, Engineering School of Lorena – University of São Paulo Area I – Lorena-SP – Brazil
https://orcid.org/0000-0002-1633-5775

Pramod Ingle

Department of Biotechnology, SGB Amravati University, Amravati-444602, Maharashtra, India
https://orcid.org/0000-0003-2801-6939


Abstract

Endophytes are those inhabiting in plants without causing any apparent loss to the host plant. Phoma is a ubiquitously found genus of fungi in soil, water and air. Endophytic Phoma spp. are distributed with high specific diversity, those occur in plants and are mainly responsible for the production of a vast range of secondary metabolites. These secondary metabolites or the bioactive compounds have demonstrated a wide range of activity ranging from antibacterial, antifungal, antiviral, algicidal, cytotoxic, antitubercular and plant growth promoting, etc. Bioactive compounds are produced by Phoma herbarum, P. sorghina, P. exigua, P. macrostoma, P. medicaginis, P. betae, P. tropica and others. The present review emphasizes on different species of endophytic Phoma as novel source of bioactive compounds, and their applications in medicine and agriculture are documented.

Keywords:

endophytes, Phoma, secondary metabolites, bioactive compounds, antimicrobial and cytotoxic activities

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Published
2020-12-31



Mahendra Rai 
Department of Biotechnology, SGB Amravati University, Amravati-444602, Maharashtra, India https://orcid.org/0000-0003-0291-0422
Aniket Gade 
Department of Biotechnology, SGB Amravati University, Amravati-444602, Maharashtra, India https://orcid.org/0000-0002-1966-999X
Beata Zimowska 
Department of Plant Protection, Institute of Plant Pathology and Mycology, University of Life Sciences in Lublin, 7 K. St. Leszczyńskiego Street, 20-068 Lublin, Poland https://orcid.org/0000-0001-5524-7623
Avinash P. Ingle 
Department of Biotechnology, Engineering School of Lorena – University of São Paulo Area I – Lorena-SP – Brazil https://orcid.org/0000-0002-1633-5775
Pramod Ingle 
Department of Biotechnology, SGB Amravati University, Amravati-444602, Maharashtra, India https://orcid.org/0000-0003-2801-6939



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